senile purpura and alcohol

National Library of Medicine. Its slightly more common in adults than in children. MedicineNet does not provide medical advice, diagnosis or treatment. Cureus. Asif M, Quiroga L, Lagziel T, Ladd SB, Caffrey J. Before each of the four treatments, and 1 month after the last treatment, the subjects' number and square area of ecchymoses will be measured by an evaluator and . 2010 Sep22(5):598-602. Schamberg's purpura in children: a review of 13 cases. In: StatPearls [Internet]. In most cases, purpura isnt serious and goes away with treatment. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. 1189-91. Cleveland Clinic is a non-profit academic medical center. Leukocytoclastic or IgA vasculitis (formerly called Henoch-Schnlein purpura) are among the types of vasculitis that can cause purpura. Malonne H, Coffiner M, Sonet B, Sereno A, Vanderbist F. Clin Ther. These appear as multiple lesions, often symmetrically involving distal extremities, areas of pressure and lips, ears, nose and trunk. New lesions appear without recognized trauma and then resolve over several days, leaving a brownish discoloration caused by deposits of hemosiderin. Use to remove results with certain terms They may also be a sign of abuse. Such a peculiarity was observed in a 55-year-old man with a 30-year history of heavy alcohol use. Its common in older adults. Reamy BV, Servey JT, Williams PM. NCI CPTC Antibody Characterization Program, Ruocco V, Psilogenis M, Lo Schiavo A, Wolf R. Dermatological manifestations of alcoholic cirrhosis. You may notice them on your skin or mucous membranes (e.g., inside your mouth). This may be considered where there are episodes of inexplicable bleeding/bruising. It's sometimes called actinic purpura. doi: 10.1016/S0738-081X(99)00033-4. Phellodendron and Citrus extracts benefit cardiovascular health in osteoarthritis patients: a double-blind, placebo-controlled pilot study. Senile purpura, also known as Bateman's purpura or actinic purpura, is a condition that commonly affects aging skin. If purpura is caused by a bleeding problem, you may have bleeding in other parts of your body. We do not endorse non-Cleveland Clinic products or services. Bateman's Purpura and How It Causes Bruising in the Elderly - Skin Site Careers. Small lesions (< 2 mm) are termed petechiae, and large lesions are termed ecchymoses or bruises. Henoch-Schonlein purpura can also cause abdominal . Dosage of drugs is not considered in the study. Our expert physicians and surgeons provide a full range of dermatologic, reconstructive and aesthetic treatments options at Cleveland Clinic. 18,201 people reported to have side effects when taking Alcohol. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. How to Increase Your Platelet Count Naturally, The Function of Blood Platelets or Thrombocytes. Sometimes, treatment isnt needed and the purpura goes away on its own. Senile Purpura - Hematology and Oncology - Merck Manuals Professional The others do. Get useful, helpful and relevant health + wellness information. There are many different types of purpura. Senile purpura is usually seen on areas exposed to mild repeated trauma, such as the back of hands. 2006 Oct8(10):672-4. Purpura can indicate a platelet count below 30 x 10. A dark blue spot on the skin can look like purpura. -. Actinic purpura results from sun-induced damage to the connective tissue of the dermis. Pediatr Dermatol. Drugs or medications that affect platelet function or clotting. The main types of purpura are defined by whether platelets are involved. doi: 10.1002/14651858.CD005128.pub3. Applying pressure to the area doesnt affect the color (blanching the skin). They may ask about your family and personal health history, such as when the spots first appeared. Your risk is also increased if you have a condition, or take medicine, that prevents platelets from working correctly. Mayo Clinic does not endorse companies or products. A single copy of these materials may be reprinted for noncommercial personal use only. They look red or purple on lighter skin tones but appear brown or black on darker skin tones. Bethesda, MD 20894, Web Policies Advertising on our site helps support our mission. Bookshelf Clin Dermatol. Senile purpura is different than conditions that cause easy bruising, due to bleeding disorders. Pronunciation of senile purpura with 1 audio pronunciations. National Institutes of Health, U.S. National Institute of Medicine: National Institutes of Health, U.S. National Institute of Medicine: MedlinePlus. Treatment depends on the cause. A six-week, randomized, multicenter, placebo-controlled, double-blind study was conducted to determine whether a uniquely formulated, oral citrus bioflavonoid supplement could treat active lesions of senile purpura while preventing new lesions from arising. Curr Opin Rheumatol. Accessed May 13, 2019. Purpura is small, flat spots on your skin. 1983;22:50610. A person with nonthrombocytopenic purpura has platelet levels in a normal range. Very difficult. Senile purpura | DermNet Petechiae vs. Purpura: What Skin Discoloration Can Tell You About Your Health. government site. This site needs JavaScript to work properly. Can purpura appear as a purple dot on the lips? https://patient.info/doctor/purpuric-rashes. It is caused by atrophy of the collagen fibres supporting blood vessels in the skin. It is unusual for purpura to emerge as a result of drinking alcohol. Purpura is a physical sign of an. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Autoantibody screen for connective tissue disorders. Thrombocytopenic purpura causes tiny purple or dark dots, and larger patches. Contact your healthcare provider if you notice purpura or any blood spots, patches or skin discoloration. Zdravic D, Yougbare I, Vadasz B, Li C, Marshall AH, Chen P, Kjeldsen-Kragh J, Ni H. Fetal and neonatal alloimmune thrombocytopenia. Oben J, Enonchong E, Kothari S, Chambliss W, Garrison R, Dolnick D. Nutr J. Petechiae are tiny, dot-like purpura. 2022 Mar 3;14(3):e22791. Complications associated with Henoch-Schonlein purpura include: Connect with others like you for support and answers to your questions in the Blood Cancers & Disorders support group on Mayo Clinic Connect, a patient community. Last reviewed by a Cleveland Clinic medical professional on 04/13/2022. An adult Caucasian alcohol-dependent patient who developed purpura after drinking alcohol was clinically observed from May 2005 to April 2016 at our institution (Table 1).The last 2 years ("purpuric phase"; cf. Predisposing factors include the influence of ultraviolet radiation, anticoagulant therapy. Other serious (but rare) types of purpura require emergency medical treatment. a decrease in flexibility, strength, or endurance. Henoch-Schonlein purpura (HSP or anaphylactoid purpura), a type of blood vessel inflammation, results in rash, arthritis, and occasional abdominal cramping. Erratum to: Recurrent purpura due to alcohol-related Schamberg's disease and its association with serum immunoglobulins: a longitudinal observation of a heavy drinker. Purpura is between 4 millimeters (mm) and 10 mm in diameter. Purpuric rashes at admission ( a, b ) and blanched lesions with confluent, Histology of the skin biopsy. 2000;43(1 Pt 1):118. 2018 Jan;11(1):13-18. Henoch-Schonlein purpura can affect anyone, but it's most common in children under 10. Goto A, Iwata T, Nozawa S, Akiyama H. Humeral Diaphyseal Osteolytic Lesion as the Initial Presentation of Acute Myeloid Leukemia in a Child: A Case Report and Review of the Literature. 2015 Jan 8;350:g7566. Health effects of alcohol and alcoholism. Poor blood vessel health (weak, fragile or inflamed blood vessels). That activates platelets, which causes too much clotting. With DIC there is massive ecchymosis with sharp, irregular borders of deep purple colour and an erythematous halo. Sunscreens are crucial for sun protection. The Caucasian patient was studied for 11 years during several detoxification treatments. It is based on alcohol (the active ingredients of Alcohol) and Alcohol (the brand name). Hahn D, Hodson EM, Willis NS, et al; Interventions for preventing and treating kidney disease in Henoch-Schonlein Purpura (HSP). Women have lesser collagen than men; hence, its slightly more common in women than in men. This article looks at the types, symptoms, and causes of purpura and how the condition is treated. It happens when small blood vessels leak blood under your skins surface. The site is secure. Participants were permitted to take warfarin, clopidogrel or aspirin during the study if they were on these medications previously. She has practicedin a variety of settings including pediatrics, oncology, chronic pain, and public health. Henoch-Schnlein purpura tends to occur in children. You suddenly feel lightheaded, dizzy, or weak. National Institute of Diabetes and Digestive and Kidney Diseases. Mayo Clinic is a not-for-profit organization. They happen when small blood vessels leak blood under your skins surface. Some people use alpha-hydroxy acid cream or tretinoin cream to make skin thicker. Would you like email updates of new search results? A similar appearance is also found in senile-type purpura. The .gov means its official. 2015 Aug 78:CD005128. It can be hard to stop bleeding from cuts and scrapes. Also tell him what medicines or supplements you take. A skin biopsy revealed histological features of purpura pigmentosa progressiva (termed Schamberg's disease). Purpura is commonly referred to as a blood spot under your skin. (Forty total geriatric patients were divided into two groups (those with and without purpura), and were matched for age. Thrombocytopenic purpura is caused by low platelets in the blood. The management of the various diseases is found in the respective articles. Senile purpura is a common, chronic skin condition affecting more than 10 percent of individuals over the age of 50. They include: Heparin-induced thrombocytopenia is caused by an immune response to heparin. If a child has bruising, check all over, including the anogenital area. Long-term steroid use can cause purpura by destroying collagen, which is a component of small blood vessels. It is due to the production of an antibody to a specific platelet antigen that the woman normally lacks. Some of these changes can include: bones shrinking in size or becoming weaker. Purpura, also known as skin hemorrhages or blood spots, can signal several medical problems, ranging from minor injuries to life threatening infections. Selective reduction in megakaryocytes (eg, drugs such as co-trimoxazole, chemicals, viral infections). The phase IV clinical study analyzes which people take Alcohol and have Purpura. 1999;17(4):3819. Small lesions (< 2 mm) are termed petechiae, and large lesions are termed ecchymoses or bruises. Other anticoagulants like aspirin may be used as well. The condition usually improves on its own. The phase IV clinical study analyzes which people take Alcohol and have Purpura. Henoch-Schnlein purpura (IgA vasculitis): Rapid evidence review. J Clin Aesthet Dermatol. 2022 Aug 8. Purpura can also be caused by drug interactions, vitamin deficiencies or congenital disorders. That is why you see a mixture of brown and purple spots. The others include: You may also have redness or a rash where the heparin was administered. 38. Your healthcare provider will examine you and ask about your symptoms. A representative area of skin bruising located on either the right or left forearm, hand or leg was selected from each patient and its appearance documented with a high-resolution digital photograph. Purpuric Rashes (Causes, Symptoms and Treatment) | Patient Actinic purpura is characterized by ecchymoses (skin discoloration due to bleeding underneath, typically caused by bruising) usually of the skin surfaces of the hands. The resulting bleeds and the bruises are way out of proportion to the cause. Clin Ther. In persistent or chronic cases, treatments may include: In some cases, an underlying infection may be treated. Small lesions (< 2 mm) are termed petechiae, and large lesions are termed ecchymoses or bruises. 2019 Aug;31(4):472-475. doi: 10.5021/ad.2019.31.4.472. These include Tylenol (acetaminophen) and Advil/Motrin (ibuprofen). No adverse effects were noted in both study arms by either the patients or the investigators. This content does not have an Arabic version. A purple spot on your lip might be from an allergic reaction to food or excessive chewing on the lip. Authors Soo Ick Cho 1 . Other types of purpura don't fit into these categories. If purpura is caused by an infection, you may have a fever or pain in the infected body part. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. An official website of the United States government. The appearance of purpura is quite characteristic and it does not blanch on pressure. Purpura is a flat, discolored spot on the skin caused by small blood vessels that leak and cause blood to pool under the skin's surface. We study millions of patients and 5,000 more each day. 2023 eHealthMe.com. ESR may indicate an inflammatory process. Patients develop persistent dark purple ecchymoses . Lesions keep their dark colour often for several weeks and there is no abnormality in bleeding times. Nonthrombycytopenic purpura and other types are not. J Am Acad Dermatol. Women have less collagen than men and it decreases by one percent a year in exposed and unexposed skin. Use OR to account for alternate terms o [ pediatric abdominal pain ] The glass test (diascope) is well known to patients and is very useful. On dark skin, the patches appear dark brown or black. Senile purpura, also called actinic purpura, is a benign skin condition that commonly affects older adults. MeSH eHealthMe is studying from 18,442 Alcohol users for its effectiveness, alternative drugs and more. 2003 Jan;48(1):31-3. doi: 10.1067/mjd.2003.25. It is created by eHealthMe based on reports of 18,201 people who have side effects while taking Alcohol from the FDA, and is updated regularly. Senile purpura typically affects older patients as their dermal tissues atrophy and blood vessels become more fragile. Heparin induced thrombocytopenia: diagnosis and management update. It will help you to know when to contact your healthcare provider. Manage or treat the underlying disease causing the purpura. HSP often resolves on its own. It is helpful to classify causes into vascular (non-thrombocytopenic) and thrombocytopenic disorders. Intravenous immunoglobin (IVIG) treatments to raise platelet levels fast. Once your healthcare provider determines the cause, they can: As with most treatments, there are potential side effects. Bruising Hands And Arms - American Osteopathic College of - AOCD Your blood thinner, aspirin, or other medicine may need to be stopped or changed. A similar appearance is also found in senile-type purpura. Treasure Island (FL): StatPearls Publishing; 2022 Jan. Other types of purpura don't fit into the thrombocytopenic or nonthrombocytopenic categories. Case presentation: Note the nature of the lesions - size, confluence, associated blisters (and what these contain: exudate, blood, pus). If the patient is on warfarin, check INR. Small lesions (< 2 mm) are termed petechiae, and large lesions are termed ecchymoses or bruises. HHS Vulnerability Disclosure, Help Results: Shellow WVR. To avoid sunburn, people should limit sun exposure during the peak hours of 10 a.m. to 3 p.m., wear protective clothing, and use a sunscreen. Women are commonly affected with purpura simplex Purpura Simplex Purpura simplex is increased bruising that is due to fragile blood vessels. They are written by UK doctors and based on research evidence, UK and European Guidelines. This new treatment appears to both safely and effectively diminish skin bruising in patients with senile purpura. This guidance is changing frequently. It is due to the production of an antibody to a specific platelet antigen that the woman normally lacks. doi:10.22159/ijpps.2018v10i1.22212. Cochrane Database Syst Rev. MedTerms medical dictionary is the medical terminology for MedicineNet.com. You vomit blood or material that looks like coffee grounds. Usually it is a self-limiting condition but it may respond to steroids. Enter search terms to find related medical topics, multimedia and more. Senile: Forgetting Hurtful Terms and Understanding - Healthline It is caused by atrophy of the collagen fibres supporting blood vessels in the skin. Purpura is reported only by a few people who take Alcohol. "Patients with senile purpura (SP) tend to bruise very easily and develop ecchymoses appearing most commonly on the extensor surfaces of the forearms, legs and hands following suspected trauma to those areas. J Gen Intern Med. https://emedicine.medscape.com/article/1087008-overview. Rarely, serious kidney damage can occur. https://www.uptodate.com/contents/search. Disclaimer. This condition develops as the blood vessels become fragile due to age leading to easy bruising with even minor falls causing significant bruises. Several acute viral infections also cause purpuric rashes. Purpura is reported only by a few people who take Alcohol. This content does not have an English version. Dilutional loss as might be seen following massive transfusion of stored blood. Verywell Health's content is for informational and educational purposes only. Purpura can be a sign of a severe disease or underlying condition. Purpura (purplish discoloration of the skin) is found to be associated with 1,814 drugs and 1,420 conditions by eHealthMe. A skin biopsy revealed histological features of purpura pigmentosa progressiva (termed Schamberg's disease). The skin in alcoholism. Subjects were randomized into two groups receiving either a citrus bioflavonoid blend or placebo medication, which was taken orally twice daily for six weeks. At the end of six weeks, the citrus bioflavonoid blend treated group showed a 50 percent reduction in purpura lesions from baseline. FOIA doi:10.7759/cureus.24124. Basal Cell Carcinoma Removed From President Bidens Chest, The Cutaneous Connection- Episode 35: QRPs and the Dermatology Practice, Oral Nicotinamide Not Beneficial in Preventing Skin Cancer in Organ Transplant Recipients, The Cutaneous Connection: An Inside Look of the Inclusive Atlas, FDA Approves First-of-Its-Kind Medical Device for Second-Degree Burn Care. It's been seen with some types of acute myeloid leukemia (AML), in both adults and children. You see more bruises or red or purple spots on your skin. generic drugs) are not considered. IgA Vasculitis. Purpura refers to purplish cutaneous or mucosal lesions caused by hemorrhage. doi:10.7759/cureus.20883. Low platelet (a blood cell that stops your body from bleeding) levels Platelets that do not work correctly Injury to blood vessels Fragile or weak blood vessels An allergic reaction to a blood transfusion Senile Purpura - Causes, Symptoms, Diagnosis and Treatment If you are a Mayo Clinic patient, this could It's also been seen with chronic lymphocytic leukemia (CLL) and T-cell large granular lymphocyte leukemia (T-LGL). The benign character of the purpura was supported by missing circulating immune complexes or complement activation. Kitchens CS. See this image and copyright information in PMC. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Serious acute complications include central nervous system (CNS) bleeding, acute intussusception or acute kidney injury. These include: Chemotherapy drugs can damage platelets, as well. A person with thrombocytopenic purpura has low platelet counts. Effective Treatment of Senile Purpura | Herbal Medicine Actinic purpura results from sun-induced damage to the connective tissue of the dermis (deeper layers of the skin) combined with the fact that the blood vessels become thinner and more fragile and collagen decreases with increasing age. The use of the eHealthMe site and its content is at your own risk. Discuss these with your healthcare provider to make sure you know what to expect. Henoch-Schonlein purpura (also known as IgA vasculitis) is a disorder that causes the small blood vessels in your skin, joints, intestines and kidneys to become inflamed and bleed. An alcohol provocation test with vinegar was followed by the development of fresh "cayenne pepper" spots characteristic of Schamberg's disease. The site is secure. To date, there are no known effective treatments for this condition. 2016 Feb;21(1):19-27. doi:10.1016/j.siny.2015.12.004. During the last 2 years of that period, purpuric rashes were newly observed. Purpura is more likely to appear in the mouth's inner lining. They may be raised or flat, and different sizes. Immunosuppressive medicines (such as rituximab [Rituxan] or azathioprine [Azasan]) to stop your immune system from destroying platelets. Senile Purpura: Clinical Features and Related Factors. Sun damage to the skin from exposure to ultraviolet rays is a risk factor for skin cancer and melanoma. See additional information. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. 8600 Rockville Pike information and will only use or disclose that information as set forth in our notice of Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. IgA vasculitis (Henoch-Schonlein purpura): Management. Take the Sun Safety Quiz and learn how to protect yourself during fun in the sun. Boynton Beach, Fla. - A new experimental oral medication known as Purpurex (New Vitality) is effective in improving and even clearing the appearance of senile purpura, while helping to prevent new lesions from occurring, according to a recent study. Purpura can develop anywhere on your skin. National Institutes of Health, National Heart, Lung, and Blood Institute. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Coagulation problems (eg, disseminated intravascular coagulation (DIC), immune thrombocytopenia, Sequestration of the platelets as occurs in. To provide you with the most relevant and helpful information, and understand which D'Addario SF, Bryan ME, Stringer WA, Johnson SM. Heparin-induced thrombocytopenia needs immediate treatment. National Institutes of Health, U.S. National Library of Medicine: MedlinePlus. Boynton Beach, Fla. - A new experimental oral medication known as Purpurex (New Vitality) is effective in improving and even clearing the appearance of senile purpura, while helping to prevent new lesions from occurring, according to a recent study. You have bleeding from your gums, mouth, or nose. Theyll take note of the size and color of the purpura and ask you when they first appeared. Objectives: Heparin-induced thrombocytopenia requires immediate treatment. PMC hurricane elizabeth 2015; cheap houses for sale in madison county; stifel wealth tracker login; zadna naprava peugeot 206; 3 days a week half marathon training plan; Warfarin may be used to clear up blood clots. It is often preceded by an upper respiratory tract infection due to beta-haemolytic streptococcal infection. UpToDate These lists are far from exhaustive (see 'Diseases associated with a purpuric rash', below) but account for the more common causes. Purpura is commonly referred to as a blood spot under your skin. They may represent severe emotional or psychiatric disturbance. Henoch-Schonlein purpura (also known as IgA vasculitis) is a disorder that causes the small blood vessels in your skin, joints, intestines and kidneys to become inflamed and bleed. Conclusions: Causes of nonthrombocytopenic purpura can include: Senile purpura is caused by thinning and weakening skin and blood vessels. Phellodendron and Citrus extracts benefit joint health in osteoarthritis patients: a pilot, double-blind, placebo-controlled study. o [teenager OR adolescent ], (See also Overview of Vascular Bleeding Disorders Overview of Vascular Bleeding Disorders Bleeding may result from abnormalities in Platelets Coagulation factors Blood vessels Vascular bleeding disorders result from defects in blood vessels, typically causing petechiae, purpura, read more .). For example, if purpura is related to a blood clotting disorder or low platelet levels, it can put your life at risk. doi: 10.1067/mjd.2000.104512. It can look like both. BMJ. This site complies with the HONcode standard for trustworthy health information: verify here. If you have a large amount of bleeding, you may need a blood transfusion, medicines, or surgery to stop the bleeding. Immune disorders such as idiopathic thrombocytopenic purpura (ITP) or. Your doctor will examine your skin to diagnose purpura. Idiopathic Thrombocytopenic Purpura. Some cases may be temporary, others longer-lasting. In this case senile means nothing more than old age, and purpura is Latin for purple, the color of the splotches. Oye M, Alkhasawneh A, Quan JR. Gamma-Delta Large Granular Lymphocytic Leukemia: A Diagnostic Dilemma. Specific risk factors for purpura are: Purpura itself doesnt usually cause complications; however, the underlying condition or disease causing purpura can. Even with wearing long sleeves while working outside, (today it was about 76 degrees by 8 AM here), I still get poked or scratched. Clinical evaluations were performed by blinded investigators at two locations. Common causes of thrombocytopenic purpura are: Common causes of nonthrombocytopenic purpura are: Purpura isnt a medical condition. Wearing protective clothing while outdoors during the day as a method of barrier protection, Carrying an umbrella or wearing a wide-brimmed hat and. Thomas Bateman, a British dermatologist, first described the condition in the year 1818. When blood vessels get inflamed, they can bleed into the skin, causing a reddish-purple rash (purpura). Purpura happen when blood leaks from blood vessels and collects under the skin or mucus membrane. Thrombopoietin receptor agonists (such as romiplostim [Nplate] or eltrombopag [Promacta]) to increase platelet levels. All rights reserved. senile purpura and alcohol Mayo Clinic. 2008 May 20;7:16. doi: 10.1186/1475-2891-7-16. Note the age of the patient. Senile purpura typically affects older patients as their dermal tissues atrophy and blood vessels become more fragile. J Clin Med. Multicenter, randomized, double-blind, active-controlled, parallel-group trial of the long-term (6-12 months) safety of acetaminophen in adult patients with osteoarthritis. Professional Reference articles are designed for health professionals to use. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Senile Purpura: Clinical Features and Related Factors - PubMed This case report demonstrates that Schamberg's disease can be strongly related to alcohol intake, in our patient most likely as a late complication of severe alcoholism with alcoholic liver disease. You may opt-out of email communications at any time by clicking on Senile purpura is a condition which is mostly seen in older adults. Allergic causes such as Henoch-Schnlein purpura, connective tissue disorders (eg. Seventy patients with senile purpura were enrolled and 67 completed the study. Use for phrases If we combine this information with your protected Nonthrombocytopenic purpura often doesn't need to be treated. Click here for an email preview. National Library of Medicine If platelet levels are OK, a skin biopsy may be the next step. Determine how long the rash has been present and whether it is changing noticeably. Henoch-Schonlein purpura - Symptoms and causes - Mayo Clinic For example, they may appear brownish-black on darker complexions and reddish-purple on lighter complexions. A condition called thrombocytopenia causes low platelets. Available for Android and iOS devices.

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